NMN inoonekwa seyakanakisaNAD+ precursor mumuviri wemunhu. Nekudaro, masayendisiti anochengetedza anotenda kuti kutorwa kweNMN kunogona zvakare kuganhurwa kune imwe nhanho. Chete nekuwedzera madosi makuru eNMN ndipo panogona kuita shanduko inoshanda.
Kuti izvi zviitike, Bangtai akabudirira kugadzira liposomeNMN, iyo escort express yeNMN, uye yakatanga kugadzirwa kwakawanda.
Chiiliposomes NMN ? Ngatitangei kutarisa kuti liposomes chii?
Liposomes ma vesicles akagadzirwa ne phospholipid mamorekuru - iwo mamorekuru akafanana anoumba maseru membranes.
Phospholipid mamorekuru ane hydrophilic phosphate musoro uye maviri hydrophobic fatty acid miswe. Aya maitiro anoita liposomes mutakuri wezvose zviri zviviri hydrophobic uye hydrophilic makomisheni.
Nekuda kwekuderera kunyura uye bioavailability yechinyakare oral dietary capsules, iyo encapsulation ye hydrophilic uye hydrophobic nutrients mu liposomes inobvumira iyo inoshanda zvinongedzo kunzvenga kuparadzwa kwe gastric system.
Kusunungura mamorekuru akadzivirirwa kunzvimbo yechiito, iyo lipid bilayer fuses nemamwe mabilayers (semuenzaniso, cell membranes), kuendesa liposomal zviri mukati zvakananga uye zvakakwana mumaseru nematishu.
Kuti zvive nyore, liposomes yakafanana nemorekuru-saizi yekutakura mari rori, inodzivirira "mari (mushonga)" iri mumotokari kubva pakubirwa munzira inoenda kuchiropa uye dzimwe nhengo.
Muchokwadi, zvigadzirwa zve liposome zvakatove nezvakawanda nyaya dzebudiriro. Vamwe vanhu vanoshandisa liposomes kuvhara Fisetin, uye bioavailability inowedzera kusvika ku27 nguva; iyo bioavailability ye liposomal vitamin B-12 formula ndeye 3-5 nguva yakakwirira kupfuura mapiritsi; liposomal berberine inogona kuwedzera kutenderera nguva23-46 nguva.
Saka, zvakakosha here kuvharidziraNMNmune liposomes?
Tichitarisa kubva kune yakasimbiswa nzira yekuita, NMN inotsamira pane slc12a8 mutakuri pamasero madiki emudumbu kuti aitakure mumasero, obva awedzera mazinga eNAD + munhengo dzakasiyana siyana uye matishu emuviri sezvo ropa richitenderera.
Nekudaro, NMN inoderedzwa nyore nyore kana hunyoro uye tembiricha zvinosvika pahurefu hwakati. Parizvino, NMN yakawanda pamusika iri muchimiro che capsules nemapiritsi. Mushure mekutora maNMN capsules kana mapiritsi, mazhinji acho anoderedzwa mudumbu. Chikamu chidiki chete cheNMN chinosvika mudumbu diki, inova hafu yemugumisiro nekuedza kaviri.
Mushure mekunge NMN yavharirwa nema liposomes, NMN inogona kuchengetedzwa kuti isvike kwainonangwa.
Chokutanga pane zvose, liposomal NMN inogona kudarika kuparara kwegadziriro yezvokudya, ichibvumira kuti ipinde zvakananga mukutenderera kweropa uye kusvika kune dzimwe nhengo dzakasiyana-siyana dzemuviri.
Kechipiri, liposomal NMN inoburitsa NMN mamorekuru kuburikidza ne membrane fusion, iyo inononoka kucheneswa kweNMN mamorekuru uye inowedzera nguva yavo yekutenderera mutsinga dzeropa, ichideredza macrophages mu reticuloendothelial system (RES) kune liposomal NMN. Digestion, uye inovandudza mwero wekuchengeta weNMN mamorekuru.
Mukuwedzera, NMN yakavharidzirwa mu liposomes inodzivirira kushandiswa kwemetabolism, uye mamorekuru emishonga anongoshanda chete mushure mokunge asvika panzvimbo yakatarwa uye kusunungurwa kubva kune liposomes.
Mukupedzisa, liposomal NMN inzira inobatsira yekudzivirira kuparara kweNMN mugastric system.
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Nguva yekutumira: Kubvumbi-16-2024
