Coenzyme Q10 ndiyo chete coenzyme Q chinhu chiri mumuviri wemunhu, inozivikanwawo seubiquinone. Coenzyme Q10 yakaratidza kuve ine antioxidant, yemahara radical scavenging, anti-bundu uye inovandudza mhedzisiro yekudzivirirwa kwevanhu, nekudaro ichibvisa kuneta nekuvandudza kugona kwekurovedza muviri, uye anti-kuchembera. Uye zvakasiyana-siyana zvehutano zvakadai sekudzivirira kwemoyo.
Poshi,Physiological mabasa e coenzyme Q10
1. Free radical scavenging uye antioxidant basa (kunonoka kuchembera uyekunakisa)
Coenzyme Q10 inowanikwa mumatunhu maviri: yakaderedzwa uye oxidized. Pakati pavo, yakaderedzwa coenzyme Q10 iri nyore oxidized uye inogona kudzivirira peroxidation ye lipids uye mapuroteni uye scavenge emahara radicals. Deredza oxidative kusagadzikana, iyo yakaipa mhedzisiro inogadzirwa nemahara radicals mumuviri uye chinhu chakakosha chinotungamira kuchembera uye chirwere. Coenzyme Q10 inoshanda antioxidant uye yemahara radical scavenger inogona kudzikamisa kukuvara kunokonzerwa neoxidative kusagadzikana.Coenzyme Q10 inogona kuvandudza bioavailability yeganda, kugadzirisa ganda, kuwedzera kuwanda kwekeratinocytes, kuvandudza iyo antioxidant kugona kwemasero eganda, inhibit kuchembera kweganda, uye kuwana kurapa mhedzisiro padermatitis, acne, bedsores, ganda maronda uye zvimwe zvirwere zveganda. Coenzyme Q10 inogonawo kukurudzira kuumbwa kwemasero epithelial uye benignization yegranulation tissue, kudzivirira kuumbwa kwevanga, uye kukurudzira kugadziriswa kwevanga; inhibisa basa re phosphotyrosinase, kudzivirira kuumbwa kwe melanin uye mavara matema; kuderedza kudzika kwemakwinya, kunatsiridza kupera kweganda; uye inogona kuwedzera kujeka Kusangana kweamino acids kunowedzera hunyoro hweganda; ine simba rakanaka pakuvandudza ganda rakasvibira, kuderedza wrinkles, uye kudzorera kutsetseka kwepakutanga kweganda, elasticity uye moisturizing properties.
2. Kuwedzera kudzivirirwa kwevanhu uye anti-bundu
Kare 1970, zvidzidzo zvakakosha zvakashuma kuti kutora coenzyme Q10 mumakonzo kunogona kuwedzera basa remasero ekudzivirira emuviri mukuuraya mabhakitiriya, kuvandudza mhinduro dzeanorwisa mabhakitiriya, uye kukurudzira kuwedzera kwenhamba ye immunoglobulins uye masoja ekudzivirira chirwere. Nikbakht et al. akadzidza kuti apo vatambi vechirume vakatora Coenzyme Q10 mushure memakwikwi akatevedzana, nhamba yeutrophils muplasma yavo yakaderedzwa zvakanyanya. Naizvozvo, vanotenda kuti Coenzyme Q10 inobatsira kuchengetedza immune system yevatambi uye kuwedzera kudzivirirwa kwemuviri. Kune vanhuwo zvavo, kutora Coenzyme Q10 nemuromo mushure mekushanda zvakanyanya kunogona kuvandudza kuneta kwemuviri uye kuwedzera simba remuviri.
Tsvagiridzo mumakore achangopfuura yakaratidza kuti coenzyme Q10, seisina-chaiyo immune system inosimudzira yemuviri, inogona kuita basa rakanaka mukuvandudza kusadzivirirwa kwemuviri uye anti-bundu, uye ine imwe kiriniki mhedzisiro pakukura metastatic cancer.
3. Simbisa simba remoyo uye kuwedzera simba rehuropi
Coenzyme Q10 chimwe chezvinhu zvakakosha zvakanyanya mumuviri wemunhu. Izvo zvirimo zvakanyanya kwazvo mumyocardium. Kana ichinge ichishaikwa, inokonzera kusakwana kushanda kwemwoyo, inotungamirira kukushaya kutenderera kweropa, kuderedza kushanda kwemoyo, uye pakupedzisira kutungamirira kuhosha yemwoyo. Mhedzisiro mikuru ye coenzyme Q10 pa myocardium ndeyekusimudzira cellular oxidative phosphorylation, kuvandudza myocardial simba metabolism, kuderedza ischemia kukuvadza kune myocardium, kuwedzera kubuda kweropa remoyo, kunatsiridza kusagadzikana kusingaperi uye kuramba arrhythmias, nokudaro kudzivirira iyo myocardium. Kuvandudza kushanda kwemoyo uye kupa simba rakakwana remyocardium. Zvidzidzo zvekiriniki zvinoratidza kuti vanopfuura 75% yevarwere vemoyo vakavandudza zvakanyanya mamiriro avo mushure mekutora Coenzyme Q10. Coenzyme Q10 is metabolic activator iyo inogona kumisa kufema kwemasero, inopa okisijeni yakakwana uye simba kune cardiomyocytes uye masero ehuropi, kuchengetedza masero mune yakanaka uye ine hutano mamiriro, uye nekudaro kudzivirira moyo uye cerebrovascular zviitiko.
4. Regulate ropa lipids
Ndichiri kudzikisa lipids eropa, ma statins anovharawo yakazvimirira yemuviri synthesis ye coenzyme Q10. Naizvozvo, vanhu vane high blood lipids vanofanira kutora coenzyme Q10 kana vachitora statins kuti vawane zviri nani lipid-kudzikisa maitiro. Coenzyme Q10 inogona kuderedza zviri mukati-density lipoprotein inokuvadza kumuviri wemunhu, kudzivirira yakaderera-density lipoprotein kubva pakupinda mukati meendothelial cell gap, kuderedza kuumbwa kwe lipids pamadziro emukati etsinga, uye kudzivirira lipids kubva pakuumba atherosclerotic. plaques pa intima yetsinga dzeropa. , nekuwedzera basa re-high-density lipoprotein, nokukurumidza kubvisa marara, chepfu uye mapepa akaumbwa pamadziro emukati emidziyo yeropa, kugadzirisa lipids yeropa uye kudzivirira kuumbwa kweatherosclerosis.
piri, Kuchengeteka kweCoenzyme Q10
Muviri wemunhu hauna mazinga akakwirira eCoenzyme Q10 pakuberekwa, asi zvinyorwa zvinosvika pakakwirira kusvika pazera remakore makumi maviri. Sezvo zera richiwedzera, iyo Coenzyme Q10 munhengo dzakasiyana uye matishu ari mumuviri inodzikira zvishoma nezvishoma, uye iyo Coenzyme Q10 iri mumoyo inoderera zvakanyanya. Kana zvirimo zveCoenzyme Q10 mumuviri wemunhu zvadzikira ne25% Mune ramangwana, zvirwere zvakasiyana zvichaitika, saka exogenous supplementation yeCoenzyme Q10 inonyanya kukosha. Chinhu chinoshamisa cheCoenzyme Q10 ndechekuti haina chepfu, haina-teratogenic uye haina mhedzisiro inooneka, uye yakachengeteka zvakanyanya pakushandiswa kwekiriniki. Coenzyme Q10, seimwe yeakanyanya kukosha coenzymes mumuviri wemunhu, iri kushandiswa zvakanyanya mukurapa.
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